LQFM030 | CAS# | p53 activator

MedKoo Cat#: 561340 | Name: LQFM030

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LQFM030 is a p53 activator that induces apoptosis in Ehrlich ascites tumour cells. LQFM030 has the potential for further development as a novel cancer therapeutic agent.

Chemical Structure

LQFM030

CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 561340

Name: LQFM030

CAS#: Unknown

Chemical Formula: C16H19ClN4O

Exact Mass: 318.1247

Molecular Weight: 318.81

Elemental Analysis: Chemical Formula: C16H19ClN4O Exact Mass: 318.1247 Molecular Weight: 318.8050 Elemental Analysis: C, 60.28; H, 6.01; Cl, 11.12; N, 17.57; O, 5.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LQFM030; LQFM-030; LQFM 030;

IUPAC/Chemical Name

1-{4-[1-(4-Chloro-phenyl)-1H-pyrazol-4-ylmethyl]-piperazin-1-yl}-ethanone

InChi Key

QHKXDHJQHJXHGV-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H19ClN4O/c1-13(22)20-8-6-19(7-9-20)11-14-10-18-21(12-14)16-4-2-15(17)3-5-16/h2-5,10,12H,6-9,11H2,1H3

SMILES Code

CC(N1CCN(CC2=CN(C3=CC=C(Cl)C=C3)N=C2)CC1)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 318.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: da Mota MF, Cortez AP, Benfica PL, Rodrigues Bdos S, Castro TF, Macedo LM, Castro CH, Lião LM, de Carvalho FS, Romeiro LA, Menegatti R, Verli H, Villavicencio B, Valadares MC. Induction of apoptosis in Ehrlich ascites tumour cells via p53 activation by a novel small-molecule MDM2 inhibitor - LQFM030. J Pharm Pharmacol. 2016 Sep;68(9):1143-59. doi: 10.1111/jphp.12573. Epub 2016 Jun 28. PubMed PMID: 27350017.