MedKoo Cat#: 565172 | Name: TR-IN-1-850
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TR-IN-1-850 is a selective blocker of T3 binding to both TRα and TRβ.

Chemical Structure

TR-IN-1-850
TR-IN-1-850
CAS#251310-57-3

Theoretical Analysis

MedKoo Cat#: 565172

Name: TR-IN-1-850

CAS#: 251310-57-3

Chemical Formula: C21H20F3N5O4

Exact Mass: 463.1467

Molecular Weight: 463.42

Elemental Analysis: C, 54.43; H, 4.35; F, 12.30; N, 15.11; O, 13.81

Price and Availability

Size Price Availability Quantity
1mg USD 350.00
5mg USD 550.00
10mg USD 800.00
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Related CAS #
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Synonym
Thyroid Hormone Receptor Antagonist (1-850); TR-IN 1-850; TR IN-1-850; TR-IN-1 850; TR-IN-1-850
IUPAC/Chemical Name
2-[1-(4-Nitrophenyl)-4-piperidinylidene]-acetic acid-2-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]hydrazide
InChi Key
CZMAYVNXNKBQKX-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H20F3N5O4/c22-21(23,24)15-2-1-3-16(13-15)25-20(31)27-26-19(30)12-14-8-10-28(11-9-14)17-4-6-18(7-5-17)29(32)33/h1-7,12-13H,8-11H2,(H,26,30)(H2,25,27,31)
SMILES Code
O=C(NNC(NC1=CC=CC(C(F)(F)F)=C1)=O)/C=C2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC/2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 463.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL