MedKoo Cat#: 561310 | Name: T-26c
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. T-26c also inhibits the breakdown of collagen in IL-1b and oncostatin M stimulated cartilage.

Chemical Structure

T-26c
T-26c
CAS#869296-13-9 (free acid)

Theoretical Analysis

MedKoo Cat#: 561310

Name: T-26c

CAS#: 869296-13-9 (free acid)

Chemical Formula: C24H21N3O6S

Exact Mass: 479.1151

Molecular Weight: 479.51

Elemental Analysis: C, 60.12; H, 4.41; N, 8.76; O, 20.02; S, 6.69

Price and Availability

Size Price Availability Quantity
50mg USD 550.00
100mg USD 950.00
200mg USD 1,650.00
500mg USD 2,450.00
1g USD 3,950.00
2g USD 6,450.00
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Synonym
T-26c, T26c, T 26c
IUPAC/Chemical Name
4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid
InChi Key
CDQRIIUMNLMHRH-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28)
SMILES Code
O=C(O)C1=CC=C(COCC2=CSC(N=C(C(NCC3=CC=CC(OC)=C3)=O)N4)=C2C4=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 479.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Florent M, Noël T, Ruprich-Robert G, Da Silva B, Fitton-Ouhabi V, Chastin C, Papon N, Chapeland-Leclerc F. Nonsense and missense mutations in FCY2 and FCY1 genes are responsible for flucytosine resistance and flucytosine-fluconazole cross-resistance in clinical isolates of Candida lusitaniae. Antimicrob Agents Chemother. 2009 Jul;53(7):2982-90. doi: 10.1128/AAC.00880-08. Epub 2009 May 4. PubMed PMID: 19414575; PubMed Central PMCID: PMC2704628.