Kanamycin B | CAS#4696-76-8 | protein translation inhibitor | mammalian RNA splicing

MedKoo Cat#: 540254 | Name: Kanamycin B

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kanamycin B is an inhibitor of protein translation and mammalian RNA splicing. It inhibits growth of gram negative bacteria, prevents formulation of the initiation complex, and decreases action potential amplitude in cardiac pacemaker cells.

Chemical Structure

Kanamycin B

CAS#4696-76-8 (free base)

Theoretical Analysis

MedKoo Cat#: 540254

Name: Kanamycin B

CAS#: 4696-76-8 (free base)

Chemical Formula: C18H37N5O10

Exact Mass: 483.2540

Molecular Weight: 483.51

Elemental Analysis: C, 44.71; H, 7.71; N, 14.48; O, 33.09

Price and Availability

Size	Price	Availability
100mg	USD 250.00	2 Weeks
250mg	USD 450.00	2 Weeks
1g	USD 850.00	2 Weeks

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Related CAS #

4696-76-8 (free base) 29701-07-3 (sulfate)

Synonym

Bekanamycin; Bekanamycin free base; NK-1006; NK1006; NK 1006; Nebramycin V; Kanamycin B; Kanendomycin;

IUPAC/Chemical Name

(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol

InChi Key

SKKLOUVUUNMCJE-FQSMHNGLSA-N

InChi Code

InChI=1S/C18H37N5O10/c19-2-6-11(26)12(27)9(23)17(30-6)32-15-4(20)1-5(21)16(14(15)29)33-18-13(28)8(22)10(25)7(3-24)31-18/h4-18,24-29H,1-3,19-23H2/t4-,5+,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1

SMILES Code

NC[C@H]1O[C@@H]([C@@H]([C@H]([C@@H]1O)O)N)O[C@@H]2[C@H](C[C@H]([C@@H]([C@H]2O)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)N)O)CO)N)N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 483.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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