VUF8507 | CAS#112575-48-1 | Adenosine Receptor Allosteric Modulator

MedKoo Cat#: 532957 | Name: VUF8507

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF8507 is an allosteric modulation of adenosine receptor.

Chemical Structure

VUF8507

CAS#112575-48-1

Theoretical Analysis

MedKoo Cat#: 532957

Name: VUF8507

CAS#: 112575-48-1

Chemical Formula: C21H15N3O

Exact Mass: 325.1215

Molecular Weight: 325.37

Elemental Analysis: C, 77.52; H, 4.65; N, 12.91; O, 4.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

VUF8507, VUF 8507, VUF-8507

IUPAC/Chemical Name

N-(3-pyridin-2-ylisoquinolin-1-yl)benzamide

InChi Key

FWRPUFITEHOETQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H15N3O/c25-21(15-8-2-1-3-9-15)24-20-17-11-5-4-10-16(17)14-19(23-20)18-12-6-7-13-22-18/h1-14H,(H,23,24,25)

SMILES Code

O=C(NC1=NC(C2=NC=CC=C2)=CC3=C1C=CC=C3)C4=CC=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 325.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gao ZG, Van Muijlwijk-Koezen JE, Chen A, Müller CE, Ijzerman AP, Jacobson KA. Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives. Mol Pharmacol. 2001 Nov;60(5):1057-63. PubMed PMID: 11641434; PubMed Central PMCID: PMC3953614. 2: van Muijlwijk-Koezen JE, Timmerman H, Link R, van der Goot H, Ijzerman AP. A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem. 1998 Oct 8;41(21):3994-4000. PubMed PMID: 9767637.