MedKoo Cat#: 127350 | Name: C12-TLRa
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

C12-TLRa is an adjuvant lipidoid (pKa = 6.42) with toll-like receptor 7/8 (TLR7/8) agonist activity.

Chemical Structure

C12-TLRa
C12-TLRa
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 127350

Name: C12-TLRa

CAS#: N/A

Chemical Formula: C46H73N5O2

Exact Mass: 727.5764

Molecular Weight: 728.12

Elemental Analysis: C, 75.88; H, 10.11; N, 9.62; O, 4.39

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
10mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
C12-TLRa; C12TLRa; C12-TL-Ra; C12 TLRa; C12-Toll-Like Receptor a
IUPAC/Chemical Name
1,1'-((4-((4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl)benzyl)azanediyl)bis(dodecan-2-ol)
InChi Key
HIHJXHDBDZYVSP-UHFFFAOYSA-N
InChi Code
InChI=1S/C46H73N5O2/c1-4-7-10-12-14-16-18-20-24-39(52)35-50(36-40(53)25-21-19-17-15-13-11-8-5-2)33-37-29-31-38(32-30-37)34-51-43(28-9-6-3)49-44-45(51)41-26-22-23-27-42(41)48-46(44)47/h22-23,26-27,29-32,39-40,52-53H,4-21,24-25,28,33-36H2,1-3H3,(H2,47,48)
SMILES Code
NC1=NC2=CC=CC=C2C3=C1N=C(N3CC4=CC=C(C=C4)CN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC)CCCC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 728.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL