UK-356618 is a selective antagonist of the CB1 receptor (cannabinoid receptor 1), which is part of the endocannabinoid system involved in regulating various physiological processes, including appetite, pain, mood, and memory. By inhibiting CB1 receptor activity, UK-356618 can reduce the effects of cannabinoids, such as appetite stimulation and the euphoric feeling associated with cannabis use. It has been investigated for its potential in the treatment of obesity and metabolic disorders, as well as in neurological conditions where CB1 activation may contribute to disease pathology. UK-356618 is a part of ongoing research into cannabinoid-based therapies that target specific receptors to avoid side effects related to broader endocannabinoid system modulation.
MedKoo Cat#: 532871
Name: UK-356618
CAS#: 230961-08-7
Chemical Formula: C34H43N3O4
Exact Mass: 557.3254
Molecular Weight: 557.74
Elemental Analysis: C, 73.22; H, 7.77; N, 7.53; O, 11.47
The following data is based on the product molecular weight 557.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
