MedKoo Cat#: 532860 | Name: UCL-1848 trifluoroacetate salt

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UCL-1848 trifluoroacetate salt is a selective Ca2+-activated, SK potassium channel blocker.

Chemical Structure

UCL-1848 trifluoroacetate salt
UCL-1848 trifluoroacetate salt
CAS#201147-53-7

Theoretical Analysis

MedKoo Cat#: 532860

Name: UCL-1848 trifluoroacetate salt

CAS#: 201147-53-7

Chemical Formula: C28H34N42+

Exact Mass: 426.2772

Molecular Weight: 426.61

Elemental Analysis: C, 78.83; H, 8.03; N, 13.13

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
UCL1848, UCL-1848, UCL 1848, UCL-1848 trifluoroacetate salt
IUPAC/Chemical Name
8,14-Diaza-1,7(1,4)-diquinolinacyclotetradecaphane trifluoroacetate salt
InChi Key
IOXVWOJJNCBJBX-XDHTVYJESA-P
InChi Code
InChI=1S/C28H32N4/c1-7-17-29-25-15-21-31(27-13-5-3-11-23(25)27)19-9-2-10-20-32-22-16-26(30-18-8-1)24-12-4-6-14-28(24)32/h3-6,11-16,21-22H,1-2,7-10,17-20H2/p+2/b29-25+,30-26+
SMILES Code
c1(NCCCCCNc2c(cccc3)c3[n+]4cc2)c5ccccc5[n+](CCCCC4)cc1
Appearance
White to off-white solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 426.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Abdullaev IF, Rudkouskaya A, Mongin AA, Kuo YH. Calcium-activated potassium channels BK and IK1 are functionally expressed in human gliomas but do not regulate cell proliferation. PLoS One. 2010 Aug 20;5(8):e12304. doi: 10.1371/journal.pone.0012304. PubMed PMID: 20808839; PubMed Central PMCID: PMC2924897. 2: Lopez de Armentia M, Sah P. Firing properties and connectivity of neurons in the rat lateral central nucleus of the amygdala. J Neurophysiol. 2004 Sep;92(3):1285-94. Epub 2004 May 5. PubMed PMID: 15128752. 3: Faber ES, Sah P. Physiological role of calcium-activated potassium currents in the rat lateral amygdala. J Neurosci. 2002 Mar 1;22(5):1618-28. PubMed PMID: 11880492. 4: Shah M, Haylett DG. The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30. PubMed PMID: 10683185; PubMed Central PMCID: PMC1571896.