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MedKoo Cat#: 525400 | Name: AJS1669

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AJS1669 is a novel muscle glycogen synthase activator, improving glucose metabolism and reducing body fat mass in mice.

Chemical Structure

AJS1669
AJS1669
CAS#1853130-05-8 (free acid)

Theoretical Analysis

MedKoo Cat#: 525400

Name: AJS1669

CAS#: 1853130-05-8 (free acid)

Chemical Formula: C26H20F2NNaO6S

Exact Mass: 535.0877

Molecular Weight: 535.49

Elemental Analysis: C, 58.32; H, 3.76; F, 7.10; N, 2.62; Na, 4.29; O, 17.93; S, 5.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
1853130-05-8 (free acid)
Synonym
AJS1669; AJS-1669; AJS 1669
IUPAC/Chemical Name
Sodium 2-[[5-[[4-(4,5-difluoro-2-methylsulfanyl-phenyl)phenoxy] methyl]furan-2-carbonyl]-(2-furylmethyl)amino]acetate
InChi Key
HGRHNLODARQRCX-UHFFFAOYSA-M
InChi Code
InChI=1S/C26H21F2NO6S.Na/c1-36-24-12-22(28)21(27)11-20(24)16-4-6-17(7-5-16)34-15-19-8-9-23(35-19)26(32)29(14-25(30)31)13-18-3-2-10-33-18;/h2-12H,13-15H2,1H3,(H,30,31);/q;+1/p-1
SMILES Code
O=C([O-])CN(C(C1=CC=C(COC2=CC=C(C3=CC(F)=C(F)C=C3SC)C=C2)O1)=O)CC4=CC=CO4.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 535.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nakano K, Takeshita S, Kawasaki N, Miyanaga W, Okamatsu Y, Dohi M, Nakagawa T. AJS1669, a novel small-molecule muscle glycogen synthase activator, improves glucose metabolism and reduces body fat mass in mice. Int J Mol Med. 2017 Apr;39(4):841-850. doi: 10.3892/ijmm.2017.2909. Epub 2017 Mar 7. PubMed PMID: 28290602; PubMed Central PMCID: PMC5360432.