SR48527 | CAS#156579-04-3 | NTS1R Antagonist

MedKoo Cat#: 532781 | Name: SR48527

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SR48527 is a NTS1R selective antagonist

Chemical Structure

SR48527

CAS#156579-04-3

Theoretical Analysis

MedKoo Cat#: 532781

Name: SR48527

CAS#: 156579-04-3

Chemical Formula: C29H29ClN4O5

Exact Mass: 548.1826

Molecular Weight: 549.02

Elemental Analysis: C, 63.44; H, 5.32; Cl, 6.46; N, 10.21; O, 14.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

SR48527; SR 4852; SR-48527.

IUPAC/Chemical Name

(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid

InChi Key

PXNTUYAGLGTUKX-MHZLTWQESA-N

InChi Code

InChI=1S/C29H29ClN4O5/c1-38-24-9-6-10-25(39-2)26(24)23-16-21(28(35)32-27(29(36)37)17-7-4-3-5-8-17)33-34(23)22-13-14-31-20-15-18(30)11-12-19(20)22/h6,9-17,27H,3-5,7-8H2,1-2H3,(H,32,35)(H,36,37)/t27-/m0/s1

SMILES Code

O=C(O)[C@@H](NC(C1=NN(C2=CC=NC3=CC(Cl)=CC=C23)C(C4=C(OC)C=CC=C4OC)=C1)=O)C5CCCCC5

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 549.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Fan Y, Lai MH, Sullivan K, Popiolek M, Andree TH, Dollings P, Pausch MH. The identification of neurotensin NTS1 receptor partial agonists through a ligand-based virtual screening approach. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5789-91. doi: 10.1016/j.bmcl.2008.09.075. Epub 2008 Sep 24. PubMed PMID: 18849166.