MedKoo Cat#: 530597 | Name: KB-NB77-78
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

KB-NB77-78 is an analog of CID797718, which is a by-product of the synthesis of the parental compound, CID755673 (PKD1 inhibitor).

Chemical Structure

KB-NB77-78
KB-NB77-78
CAS#1350622-33-1

Theoretical Analysis

MedKoo Cat#: 530597

Name: KB-NB77-78

CAS#: 1350622-33-1

Chemical Formula: C18H25NO3Si

Exact Mass: 331.1604

Molecular Weight: 331.49

Elemental Analysis: C, 65.22; H, 7.60; N, 4.23; O, 14.48; Si, 8.47

Price and Availability

Size Price Availability Quantity
1g USD 3,450.00 4 Weeks
2g USD 4,650.00 4 Weeks
5g USD 7,850.00 4 Weeks
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Related CAS #
No Data
Synonym
kb-NB77-78; kb-NB-77-78; kb-NB 77-78; kb-NB7778; kb-NB-7778; kb-NB 7778;
IUPAC/Chemical Name
9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-b]pyridin-5-one
InChi Key
UNMWMPXUIXEQJZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H25NO3Si/c1-18(2,3)23(4,5)22-12-8-9-15-14(11-12)13-7-6-10-19-16(13)17(20)21-15/h8-9,11,19H,6-7,10H2,1-5H3
SMILES Code
O=C1OC2=CC=C(O[Si](C)(C(C)(C)C)C)C=C2C3=C1NCCC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
George KM, Frantz MC, Bravo-Altamirano K, Lavalle CR, Tandon M, Leimgruber S, Sharlow ER, Lazo JS, Wang QJ, Wipf P. Design, Synthesis, and Biological Evaluation of PKD Inhibitors. Pharmaceutics. 2011;3(2):186-228. doi: 10.3390/pharmaceutics3020186. PMID: 22267986; PMCID: PMC3261798.