MedKoo Cat#: 529213 | Name: KDT 501 potassium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KDT 501 is a PPAR agonist and G protein-coupled receptor (GPR) 120 agonist potentially for the treatment of type 2 diabetes.

Chemical Structure

KDT 501 potassium
KDT 501 potassium
CAS#1374259-84-3 (potassium)

Theoretical Analysis

MedKoo Cat#: 529213

Name: KDT 501 potassium

CAS#: 1374259-84-3 (potassium)

Chemical Formula: C21H33KO5

Exact Mass:

Molecular Weight: 404.59

Elemental Analysis: C, 62.34; H, 8.22; K, 9.66; O, 19.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
KDT-501; KDT 501; KDT 501; KDT 501 potassium salt; Tetrahydroisohumulone.
IUPAC/Chemical Name
potassium (1S,5R)-2-hydroxy-5-isopentyl-3-(3-methylbutanoyl)-1-(4-methylpentanoyl)-4-oxocyclopent-2-en-1-olate
InChi Key
OBRIOHODJVKWGS-QWABXWKJSA-N
InChi Code
InChI=1S/C21H33O5.K/c1-12(2)7-9-15-19(24)18(16(22)11-14(5)6)20(25)21(15,26)17(23)10-8-13(3)4;/h12-15,25H,7-11H2,1-6H3;/q-1;+1/t15-,21+;/m0./s1
SMILES Code
O=C1C(C(CC(C)C)=O)=C(O)[C@@](C(CCC(C)C)=O)([O-])[C@H]1CCC(C)C.[K+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 404.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Konda VR, Desai A, Darland G, Grayson N, Bland JS. KDT501, a derivative from hops, normalizes glucose metabolism and body weight in rodent models of diabetes. PLoS One. 2014 Jan 30;9(1):e87848. doi: 10.1371/journal.pone.0087848. PubMed PMID: 24498211; PubMed Central PMCID: PMC3907559.