NPD926 is an inducer of cancel cell death. NPD926 sensitized cells to inhibitors of system x(c)⁻, a cystine-glutamate antiporter considered to be a potential therapeutic target in cancers including cancer stem cells. Induction of excessive levels of reactive oxygen species (ROS) by small-molecule compounds has been considered a potentially effective therapeutic strategy against cancer cells, which are often subjected to chronic oxidative stress.
MedKoo Cat#: 407391
Name: NPD926
CAS#: 384361-79-9
Chemical Formula: C29H35ClN2O2
Exact Mass: 478.2387
Molecular Weight: 479.06
Elemental Analysis: C, 72.71; H, 7.36; Cl, 7.40; N, 5.85; O, 6.68
The following data is based on the product molecular weight 479.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
