SPM-242 is an orthosteric agonist of S1P and a novel bitopic antagonist. Sphingosine 1-phosphate (S1P) is a lysophospholipid signaling molecule that regulates important biological functions, including lymphocyte trafficking and vascular development, by activating G protein-coupled receptors for S1P, namely, S1P(1) through S1P(5).
MedKoo Cat#: 530506
Name: SPM-242
CAS#: 2733813-95-9 (s-isomer)
Chemical Formula: C17H21ClNO6PS
Exact Mass: 433.0516
Molecular Weight: 433.84
Elemental Analysis: C, 47.07; H, 4.88; Cl, 8.17; N, 3.23; O, 22.13; P, 7.14; S, 7.39
The following data is based on the product molecular weight 433.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
