MedKoo Cat#: 529615 | Name: Dimiracetam

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimiracetam is a NMDA-receptor antagonist potentially for the treatment of neuropathic pain

Chemical Structure

Dimiracetam
CAS#126100-97-8

Theoretical Analysis

MedKoo Cat#: 529615

Name: Dimiracetam

CAS#: 126100-97-8

Chemical Formula: C6H8N2O2

Exact Mass: 140.0586

Molecular Weight: 140.14

Elemental Analysis: C, 51.42; H, 5.75; N, 19.99; O, 22.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NT-11624; BND-11624; ISF-4185; NT11624; BND11624; ISF4185; NT 11624; BND 11624; ISF 4185
IUPAC/Chemical Name
tetrahydro-5H-pyrrolo[1,2-a]imidazole-2,5(3H)-dione
InChi Key
XTXXOHPHLNROBN-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H8N2O2/c9-5-3-8-4(7-5)1-2-6(8)10/h4H,1-3H2,(H,7,9)
SMILES Code
O=C1NC(CCC2=O)N2C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 140.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Di Cesare Mannelli L, Maresca M, Farina C, Scherz MW, Ghelardini C. A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam. Neurotoxicology. 2015 Sep;50:101-7. doi: 10.1016/j.neuro.2015.08.002. PubMed PMID: 26254739. 2: Fariello RG, Ghelardini C, Di Cesare Mannelli L, Bonanno G, Pittaluga A, Milanese M, Misiano P, Farina C. Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain. Neuropharmacology. 2014 Jun;81:85-94. doi: 10.1016/j.neuropharm.2014.01.029. PubMed PMID: 24486381. 3: Farina C, Gagliardi S, Ghelardini C, Martinelli M, Norcini M, Parini C, Petrillo P, Ronzoni S. Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain. Bioorg Med Chem. 2008 Mar 15;16(6):3224-32. doi: 10.1016/j.bmc.2007.12.015. PubMed PMID: 18171618. 4: Torchio L, Lombardi F, Visconti M, Doyle E. Determination of the polar drug dimiracetam in human plasma and serum by column-switching high-performance liquid chromatography. J Chromatogr B Biomed Appl. 1995 Apr 7;666(1):169-77. PubMed PMID: 7655615. 5: Pinza M, Farina C, Cerri A, Pfeiffer U, Riccaboni MT, Banfi S, Biagetti R, Pozzi O, Magnani M, Dorigotti L. Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers. J Med Chem. 1993 Dec 24;36(26):4214-20. PubMed PMID: 8277504.