MedKoo Cat#: 407351 | Name: NI-57
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

NI-57 is a potent inhibitor of the bromodomains of BRPF proteins that binds to BRPF1B, BRPF2, and BRPF3 with Kd values of 31, 108, and 408 nM, respectively

Chemical Structure

NI-57
CAS#1883548-89-7

Theoretical Analysis

MedKoo Cat#: 407351

Name: NI-57

CAS#: 1883548-89-7

Chemical Formula: C19H17N3O4S

Exact Mass: 383.0940

Molecular Weight: 383.42

Elemental Analysis: C, 59.52; H, 4.47; N, 10.96; O, 16.69; S, 8.36

Price and Availability

Size Price Availability Quantity
5mg USD 275.00 2 Weeks
10mg USD 500.00 2 Weeks
1g USD 3,650.00
2g USD 6,250.00
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Related CAS #
No Data
Synonym
NI-57; NI 57; NI57.
IUPAC/Chemical Name
4-cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)-2-methoxybenzenesulfonamide
InChi Key
UEMQPCYDWCSVCU-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H17N3O4S/c1-12-8-14-10-15(5-6-16(14)22(2)19(12)23)21-27(24,25)18-7-4-13(11-20)9-17(18)26-3/h4-10,21H,1-3H3
SMILES Code
O=S(C1=CC=C(C#N)C=C1OC)(NC2=CC3=C(N(C)C(C(C)=C3)=O)C=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 383.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL