MedKoo Cat#: 574819 | Name: NIBR-17
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NIBR-17 is a pan class I PI3K inhibitor

Chemical Structure

NIBR-17
NIBR-17
CAS#944396-88-7

Theoretical Analysis

MedKoo Cat#: 574819

Name: NIBR-17

CAS#: 944396-88-7

Chemical Formula: C18H20N8O2

Exact Mass: 380.1709

Molecular Weight: 380.41

Elemental Analysis: C, 56.83; H, 5.30; N, 29.46; O, 8.41

Price and Availability

Size Price Availability Quantity
5mg USD 375.00 2 Weeks
10mg USD 615.00 2 Weeks
25mg USD 1,140.00 2 Weeks
50mg USD 1,950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
NIBR17; NIBR 17; NIBR-17
IUPAC/Chemical Name
N6-(6-methoxypyridin-3-yl)-2-morpholino-[4,5'-bipyrimidine]-2',6-diamine
InChi Key
XZTYTIOLZIKUJR-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20N8O2/c1-27-16-3-2-13(11-20-16)23-15-8-14(12-9-21-17(19)22-10-12)24-18(25-15)26-4-6-28-7-5-26/h2-3,8-11H,4-7H2,1H3,(H2,19,21,22)(H,23,24,25)
SMILES Code
COc1ccc(cn1)Nc2cc(nc(n2)N3CCOCC3)c4cnc(nc4)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
NIBR-17 is a pan-class I PI3K inhibitor with suitable pharmacokinetic properties and inhibits tumor growth.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM comments
Solubility
DMSO 3.0 7.89
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 380.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD