MedKoo Cat#: 526446 | Name: Theofibrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Theofibrate, also known as Etofylline clofibrate, is an agent shown to lower blood lipid levels. Etofylline clofibrate is suitable for the treatment of hyperlipoproteinaemia with elevated triglycerides and cholesterol.

Chemical Structure

Theofibrate
Theofibrate
CAS#54504-70-0

Theoretical Analysis

MedKoo Cat#: 526446

Name: Theofibrate

CAS#: 54504-70-0

Chemical Formula: C19H21ClN4O5

Exact Mass: 420.1200

Molecular Weight: 420.85

Elemental Analysis: C, 54.23; H, 5.03; Cl, 8.42; N, 13.31; O, 19.01

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
Theofibrate; Etofylline clofibrate; Etofyllineclofibrate; Duolip; ML 1024; ML1024; ML-1024; NSC 234348; NSC234348; NSC-234348
IUPAC/Chemical Name
Propionic acid, 2-(4-chlorophenoxy)-2-methyl-, 2-(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-yl) ethyl ester
InChi Key
KYAKGJDISSNVPZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H21ClN4O5/c1-19(2,29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)22(15)3/h5-8,11H,9-10H2,1-4H3
SMILES Code
CC(C)(OC1=CC=C(Cl)C=C1)C(OCCN2C=NC(N(C)C(N3C)=O)=C2C3=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 420.85 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Metz G, Sim AK, McCraw AP, Cleland ME. Effect of etofylline clofibrate on experimental thrombus formation and prostacyclin activation. Arzneimittelforschung. 1986 Sep;36(9):1363-5. PMID: 3539125.