VUF16216 | CXCR3 Ligand

MedKoo Cat#: 558702 | Name: VUF16216

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF16216 is a CXCR3 ligand which photoswitches from antagonism to agonism.

Chemical Structure

VUF16216

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 558702

Name: VUF16216

CAS#: NONE

Chemical Formula: C26H33BrIN3O

Exact Mass:

Molecular Weight: 610.38

Elemental Analysis: C, 51.16; H, 5.45; Br, 13.09; I, 20.79; N, 6.88; O, 2.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

VUF-16216; VUF 16216; VUF16216

IUPAC/Chemical Name

N-(5-((E)-(2-Bromophenyl)diazenyl)-2-methoxybenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethylmethanaminium iodide

InChi Key

XRGWGEKBIQYYOO-LKGSDXNSSA-M

InChi Code

InChI=1S/C26H33BrN3O.HI/c1-26(2)20-11-10-18(22(26)15-20)16-30(3,4)17-19-14-21(12-13-25(19)31-5)28-29-24-9-7-6-8-23(24)27;/h6-10,12-14,20,22H,11,15-17H2,1-5H3;1H/q+1;/p-1/b29-28+;/t20-,22-;/m0./s1

SMILES Code

C[N+](C)(CC1=CC(/N=N/C2=CC=CC=C2Br)=CC=C1OC)CC3=CC[C@]4([H])C(C)(C)[C@@]3([H])C4.[I-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 610.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gómez-Santacana X, de Munnik SM, Vijayachandran P, Da Costa Pereira D, Bebelman JPM, de Esch IJP, Vischer HF, Wijtmans M, Leurs R. Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism. Angew Chem Int Ed Engl. 2018 Sep 3;57(36):11608-11612. doi: 10.1002/anie.201804875. Epub 2018 Aug 6. PubMed PMID: 29926530.