MedKoo Cat#: 561679 | Name: CypD inhibitor C-9

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CypD inhibitor C-9 is a CypD inhibitor that acts by binding strongly to CypD and attenuating mitochondrial and cellular perturbation insulted by Aß and calcium stress.

Chemical Structure

CypD inhibitor C-9
CypD inhibitor C-9
CAS#1572646-93-5

Theoretical Analysis

MedKoo Cat#: 561679

Name: CypD inhibitor C-9

CAS#: 1572646-93-5

Chemical Formula: C22H22N4O4S2

Exact Mass: 470.1082

Molecular Weight: 470.56

Elemental Analysis: C, 56.15; H, 4.71; N, 11.91; O, 13.60; S, 13.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
CypD inhibitor C-9; CypD inhibitor C 9; CypD inhibitor C9;
IUPAC/Chemical Name
N-[4-(Aminosulfonyl)phenyl]-2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxamide
InChi Key
XYSDAMUFZPVEAY-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H22N4O4S2/c1-13(2)12-30-19-9-4-15(10-16(19)11-23)22-25-14(3)20(31-22)21(27)26-17-5-7-18(8-6-17)32(24,28)29/h4-10,13H,12H2,1-3H3,(H,26,27)(H2,24,28,29)
SMILES Code
O=C(C1=C(C)N=C(C2=CC=C(OCC(C)C)C(C#N)=C2)S1)NC3=CC=C(S(=O)(N)=O)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 470.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Valasani KR, Sun Q, Fang D, Zhang Z, Yu Q, Guo Y, Li J, Roy A, ShiDu Yan S. Identification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial Dysfunction. ACS Med Chem Lett. 2016 Jan 6;7(3):294-9. doi: 10.1021/acsmedchemlett.5b00451. eCollection 2016 Mar 10. PubMed PMID: 26985318; PubMed Central PMCID: PMC4789676.