A331440 | CAS#392338-13-5 | receptor modulator

MedKoo Cat#: 531351 | Name: A331440

Description:

WARNING: This product is for research use only, not for human or veterinary use.

A331440 is an L-histidine and histamine H3 receptor modulator.

Chemical Structure

A331440

CAS#392338-13-5 (free base)

Theoretical Analysis

MedKoo Cat#: 531351

Name: A331440

CAS#: 392338-13-5 (free base)

Chemical Formula: C22H27N3O

Exact Mass: 349.2154

Molecular Weight: 349.48

Elemental Analysis: C, 75.61; H, 7.79; N, 12.02; O, 4.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

1049740-32-0 (HCl) 392338-13-5 (free base)

Synonym

A331440; A 331440; A-331440; A331440 free base;

IUPAC/Chemical Name

4-[4-[3-[(3R)-3-dimethylaminopyrrolidin-1-yl]propoxy]phenyl]benzonitrile

InChi Key

FXIPXWLVYIHFEP-OAQYLSRUSA-N

InChi Code

InChI=1S/C22H27N3O/c1-24(2)21-12-14-25(17-21)13-3-15-26-22-10-8-20(9-11-22)19-6-4-18(16-23)5-7-19/h4-11,21H,3,12-15,17H2,1-2H3/t21-/m1/s1

SMILES Code

N#CC1=CC=C(C2=CC=C(OCCCN3C[C@H](N(C)C)CC3)C=C2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 349.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Didone V, Quoilin C, Nyssen L, Closon C, Tirelli E, Quertemont E. Effects of L-histidine and histamine H3 receptor modulators on ethanol-induced sedation in mice. Behav Brain Res. 2013 Feb 1;238:113-8. doi: 10.1016/j.bbr.2012.10.019. PubMed PMID: 23089647.