MedKoo Cat#: 328087 | Name: Esprolol hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Esprolol, also known as ACC-9369, is a β-adrenergic receptor antagonist potentially for the treatment of angina pectoris, anxiety and migraine. Esprolol has potential for short-term use in patients with exertional angina and in patients with other diseases in which rapid-onset beta blocking action would be beneficial.

Chemical Structure

Esprolol hydrochloride
Esprolol hydrochloride
CAS#112805-65-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 328087

Name: Esprolol hydrochloride

CAS#: 112805-65-9 (HCl)

Chemical Formula: C17H28ClNO4

Exact Mass:

Molecular Weight: 345.86

Elemental Analysis: C, 59.04; H, 8.16; Cl, 10.25; N, 4.05; O, 18.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Esprolol hydrochloride; ACC-9369; ACC9369; ACC 9369.
IUPAC/Chemical Name
ethyl (S)-3-(2-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propanoate hydrochloride
InChi Key
IKFUEAAUZIWSDO-RSAXXLAASA-N
InChi Code
InChI=1S/C17H27NO4.ClH/c1-4-21-17(20)10-9-14-7-5-6-8-16(14)22-12-15(19)11-18-13(2)3;/h5-8,13,15,18-19H,4,9-12H2,1-3H3;1H/t15-;/m0./s1
SMILES Code
O=C(OCC)CCC1=CC=CC=C1OC[C@@H](O)CNC(C)C.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# 396654-09-4 (Esprolol) 112805-65-9 (Esprolol hydrochloride)

Preparing Stock Solutions

The following data is based on the product molecular weight 345.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Matier WL, Patil G. Esprolol hydrochloride: a new beta adrenergic antagonist with a rapid onset of effect. Heart Dis. 2000 Mar-Apr;2(2):146-50. PubMed PMID: 11728252.