MedKoo Cat#: 329111 | Name: Chlormidazole HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chlormidazole is an antifungal agent. It belongs to the imidazole class of antifungal drugs, which are known for their broad-spectrum activity against various fungal infections. Chlormidazole works by inhibiting the biosynthesis of ergosterol, an essential component of fungal cell membranes. This disruption compromises the integrity of the fungal cell membrane, leading to leakage of intracellular contents and eventual cell death.

Chemical Structure

Chlormidazole HCl
Chlormidazole HCl
CAS#74298-63-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 329111

Name: Chlormidazole HCl

CAS#: 74298-63-8 (HCl)

Chemical Formula: C15H14Cl2N2

Exact Mass: 0.0000

Molecular Weight: 293.19

Elemental Analysis: C, 61.45; H, 4.81; Cl, 24.18; N, 9.55

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
1g USD 2,450.00 2 Weeks
5g USD 6,950.00 2 Weeks
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Related CAS #
3689-76-7 (free base) 74298-63-8 (HCl) 760115-45-5 (free base) 54118-67-1(HCl)
Synonym
Chlormidazole Hydrochloride; H115; H 115; H-115; Myco-polycid; Futrican hydrochloride; Fungo-polycid
IUPAC/Chemical Name
1-(4-chlorobenzyl)-2-methyl-1H-benzo[d]imidazole hydrochloride
InChi Key
MHMTXDMLQZHXRZ-UHFFFAOYSA-O
InChi Code
InChI=1S/C15H13ClN2.ClH/c1-11-17-14-4-2-3-5-15(14)18(11)10-12-6-8-13(16)9-7-12;/h2-9H,10H2,1H3;1H/p+1
SMILES Code
CC1=[NH+]C2=CC=CC=C2N1CC3=CC=C(Cl)C=C3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# 3689-76-7 (Chlormidazole) 54118-67-1 (Chlormidazole Hydrochloride)

Preparing Stock Solutions

The following data is based on the product molecular weight 293.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Szymczykowa B. [Efficacy of the Myco-Polycid preparation in the form of tincture and cream for the treatment of dermatomycoses]. Mykosen. 1975 Dec;18(12):523-6. German. PubMed PMID: 129703. 2: Kubec K, Sluková M. [Clinical results in treatment of dermatomycoses with Myco-Polycid]. Cesk Dermatol. 1973 Dec;48(6):411-4. Czech. PubMed PMID: 4589249. 3: Michałowski R, Kuczyńska L, Olejnicka Z, Kucharska D, Urban J, Kosińska J. [Myco-polycid in the treatment of dermatomycoses]. Przegl Dermatol. 1978 Nov-Dec;65(6):709-14. Polish. PubMed PMID: 725113. 4: Ruszczak Z, Prószyńska-Kuczyńska W, Bielecka B. [Effectiveness of treatment of skin mycoses and tolerance to myco-polycid preparations]. Przegl Dermatol. 1978 Sep-Oct;65(5):571-5. Polish. PubMed PMID: 725101. 5: Machońko T, Wasik H, Stepień B, Skowroński M. [Myco-Polycid in the treatment of skin mycoses]. Przegl Dermatol. 1978 Jul-Aug;65(4):445-9. Polish. PubMed PMID: 693933. 6: Lukowska I. [Treatment of dermatomycoses with Myco-Polycid]. Mykosen. 1975 May;18(5):245-8. German. PubMed PMID: 1160933.