MedKoo Cat#: 526925 | Name: CL-329167

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CL-329167 is a angiotensin type 1 receptor antagonist potentially for the treatment of hypertension.

Chemical Structure

CL-329167
CL-329167
CAS#143945-39-5

Theoretical Analysis

MedKoo Cat#: 526925

Name: CL-329167

CAS#: 143945-39-5

Chemical Formula: C30H32N6O2

Exact Mass: 508.2587

Molecular Weight: 508.63

Elemental Analysis: C, 70.84; H, 6.34; N, 16.52; O, 6.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
CL-329167; CL 329167; CL329167.
IUPAC/Chemical Name
2-Butyl-6-(1-methoxy-1-methylethyl)-3-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]quinazolin-4(3H)-one
InChi Key
XZCUIMYYMKTCBA-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H32N6O2/c1-5-6-11-27-31-26-17-16-22(30(2,3)38-4)18-25(26)29(37)36(27)19-20-12-14-21(15-13-20)23-9-7-8-10-24(23)28-32-34-35-33-28/h7-10,12-18H,5-6,11,19H2,1-4H3,(H,32,33,34,35)
SMILES Code
O=C1N(CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C(CCCC)=NC5=C1C=C(C(C)(OC)C)C=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# 143945-39-5 (free) 144364-95-4 (sodium salt)

Preparing Stock Solutions

The following data is based on the product molecular weight 508.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cachofeiro V, Guan H, Nasjletti A. Contribution of nitric oxide to the acute antihypertensive effect of blockers of AT1 angiotensin receptors in spontaneously hypertensive rats. Clin Exp Hypertens. 1997 Nov;19(8):1247-61. PubMed PMID: 9385474. 2: Lopez JJ, Lorell BH, Ingelfinger JR, Weinberg EO, Schunkert H, Diamant D, Tang SS. Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts. Am J Physiol. 1994 Aug;267(2 Pt 2):H844-52. PubMed PMID: 8067441.