MK-8998 is a T type calcium channel antagonist potentially for the treatment of schizophrenia. MK-8998 was not effective in treating acutely psychotic inpatients with schizophrenia, as measured by PANSS score at week 4.
MedKoo Cat#: 526893
Name: MK-8998
CAS#: 953778-58-0 (free base)
Chemical Formula: C20H23F3N2O2
Exact Mass: 380.1712
Molecular Weight: 380.41
Elemental Analysis: C, 63.15; H, 6.09; F, 14.98; N, 7.36; O, 8.41
The following data is based on the product molecular weight 380.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
