MedKoo Cat#: 326882 | Name: Sunepitron HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sunepitron, also known as CP-93,393 or CP-93,393-1 (HCl), is a combined 5-HT1A receptor agonist and α2-adrenergic receptor antagonist. It was previously under development by Pfizer for the treatment of depression and anxiety. It made it to phase III clinical trials before being discontinued.

Chemical Structure

Sunepitron HCl
Sunepitron HCl
CAS#148408-65-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 326882

Name: Sunepitron HCl

CAS#: 148408-65-5 (HCl)

Chemical Formula: C17H24ClN5O2

Exact Mass:

Molecular Weight: 365.86

Elemental Analysis: C, 55.81; H, 6.61; Cl, 9.69; N, 19.14; O, 8.75

Price and Availability

Size Price Availability Quantity
5mg USD 305.00 2 Weeks
25mg USD 900.00 2 Weeks
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Synonym
CP-93,393; CP 93,393; CP93,393; CP-93393; CP 93393; CP93393; CP-93,393-1; Sunepitron. Sunepitron HCl.
IUPAC/Chemical Name
1-(((7S,9aS)-2-(pyrimidin-2-yl)octahydro-2H-pyrido[1,2-a]pyrazin-7-yl)methyl)pyrrolidine-2,5-dione hydrochloride
InChi Key
HWGPYTRJVVMHGT-IODNYQNNSA-N
InChi Code
InChI=1S/C17H23N5O2.ClH/c23-15-4-5-16(24)22(15)11-13-2-3-14-12-21(9-8-20(14)10-13)17-18-6-1-7-19-17;/h1,6-7,13-14H,2-5,8-12H2;1H/t13-,14-;/m0./s1
SMILES Code
O=C(N1C[C@H]2CC[C@@]3([H])CN(C4=NC=CC=N4)CCN3C2)CCC1=O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Related CAS# CAS No. 148408-65-5 (Sunepitron hydrochloride) 131831-03-3 (Sunipetron free base)

Preparing Stock Solutions

The following data is based on the product molecular weight 365.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ahsan ZS, Song Y, Yao J. Outcomes of ulnar shortening osteotomy fixed with a dynamic compression system. J Hand Surg Am. 2013 Aug;38(8):1520-3. doi: 10.1016/j.jhsa.2013.04.040. Epub 2013 Jul 3. PubMed PMID: 23830678. 2: Goodnick PJ. Psychopharmacology of depression in the next millennium. CNS Spectr. 1999 Jul;4(7):21-35. PubMed PMID: 18438295. 3: Hambire SD, Bhavsar PP, B M, Jayakar AV. Fraser-Cryptophthalmos syndrome with cardiovascular malformations: a rare association. Indian Pediatr. 2003 Sep;40(9):888-90. PubMed PMID: 14530551. 4: Spell JC, Stewart JT. Analysis of clonazepam in a tablet dosage form using smallbore HPLC. J Pharm Biomed Anal. 1998 Nov;18(3):453-60. PubMed PMID: 10096839. 5: Colgan ST, Dumont ML, Ruggeri SG. Assay and purity evaluation of sunepitron hydrochloride by reversed-phase liquid chromatography using a reference standard composite. J Pharm Biomed Anal. 1998 Nov;18(3):429-40. PubMed PMID: 10096837.