LY 201409 | CAS#109306-94-7 | anticonvulsant

MedKoo Cat#: 525508 | Name: LY 201409

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 201409 is a potent benzamide anticonvulsant. LY201409 antagonized maximal electroshock (MES)-induced seizures with ED50 values of 16.2 and 4.2 mg/kg after oral administration to mice and rats, respectively.

Chemical Structure

LY 201409

CAS#109306-94-7

Theoretical Analysis

MedKoo Cat#: 525508

Name: LY 201409

CAS#: 109306-94-7

Chemical Formula: C17H20N2O

Exact Mass: 268.1576

Molecular Weight: 268.36

Elemental Analysis: C, 76.09; H, 7.51; N, 10.44; O, 5.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

LY 201409; LY201409; LY-201409.

IUPAC/Chemical Name

Benzamide, 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethyl-

InChi Key

ZSXGPMMRFFQFCH-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H20N2O/c1-10-6-5-7-11(2)16(10)19-17(20)14-8-12(3)15(18)13(4)9-14/h5-9H,18H2,1-4H3,(H,19,20)

SMILES Code

C(c1cc(c(c(c1)C)N)C)(=O)Nc1c(cccc1C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 268.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Robertson DW, Lawson RR, Rathbun RC, Leander JD. Pharmacology of LY201409, a potent benzamide anticonvulsant. Epilepsia. 1988 Nov-Dec;29(6):760-9. PubMed PMID: 3191892. 2: Robertson DW, Leander JD, Lawson R, Beedle EE, Clark CR, Potts BD, Parli CJ. Discovery and anticonvulsant activity of the potent metabolic inhibitor 4-amino-N-(2,6-dimethylphenyl)-3,5-dimethylbenzamide. J Med Chem. 1987 Oct;30(10):1742-6. PubMed PMID: 3656350.