Orysastrobin | CAS#248593-16-0 | fungicide

MedKoo Cat#: 146262 | Name: Orysastrobin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Orysastrobin is a fungicide developed for the control of rice diseases, particularly leaf and panicle blast (Magnaporthe oryzae) and sheath blight (Thanatephorus cucumeris). It belongs to the strobilurin class of fungicides, specifically acting as a quinone outside inhibitor (QoI) by binding to the cytochrome bc1 complex in the mitochondrial electron transport chain. This binding inhibits the transfer of electrons, disrupting cellular respiration and leading to fungal cell death. Orysastrobin is systemic, providing both protective and curative effects, and is applied to rice fields to manage these fungal diseases effectively.

Chemical Structure

Orysastrobin

CAS#248593-16-0

Theoretical Analysis

MedKoo Cat#: 146262

Name: Orysastrobin

CAS#: 248593-16-0

Chemical Formula: C18H25N5O5

Exact Mass: 391.1856

Molecular Weight: 391.43

Elemental Analysis: C, 55.23; H, 6.44; N, 17.89; O, 20.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Orysastrobin;

IUPAC/Chemical Name

(E)-2-(methoxyimino)-2-(2-((3E,5E,6E)-5-(methoxyimino)-4,6-dimethyl-2,8-dioxa-3,7-diazanona-3,6-dien-1-yl)phenyl)-N-methylacetamide

InChi Key

JHIPUJPTQJYEQK-ZLHHXESBSA-N

InChi Code

1S/C18H25N5O5/c1-12(20-25-4)16(22-26-5)13(2)21-28-11-14-9-7-8-10-15(14)17(23-27-6)18(24)19-3/h7-10H,11H2,1-6H3,(H,19,24)/b20-12+,21-13+,22-16+,23-17+

SMILES Code

CNC(=O)C(=N\OC)\C1=CC=CC=C1CO\N=C(C)\C(=N\OC)\C(C)=N\OC

Appearance

To be determined

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 391.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kwon CH, Lee YD, Im MH. Simultaneous determination of orysastrobin and its isomers in rice using HPLC-UV and LC-MS/MS. J Agric Food Chem. 2011 Oct 26;59(20):10826-30. doi: 10.1021/jf202228p. Epub 2011 Oct 4. PMID: 21942277. 2: Takahashi N, Sunohara Y, Fujiwara M, Matsumoto H. Improved tolerance to transplanting injury and chilling stress in rice seedlings treated with orysastrobin. Plant Physiol Biochem. 2017 Apr;113:161-167. doi: 10.1016/j.plaphy.2017.02.004. Epub 2017 Feb 7. PMID: 28214729. 3: Alloisio S, Nobile M, Novellino A. Multiparametric characterisation of neuronal network activity for in vitro agrochemical neurotoxicity assessment. Neurotoxicology. 2015 May;48:152-65. doi: 10.1016/j.neuro.2015.03.013. Epub 2015 Apr 4. PMID: 25845298. 4: Nagai T. Sensitivity differences among five species of aquatic fungi and fungus-like organisms for seven fungicides with various modes of action. J Pestic Sci. 2020 Nov 20;45(4):223-229. doi: 10.1584/jpestics.D20-035. PMID: 33304191; PMCID: PMC7691557. 5: Wang LF, Li CM, Xu J, Li H, Su H, Wang J, Jin F, Zhang Y. [Simultaneous determination of 11 strobilurin fungicides in different vegetation types of soil by QuEChERS-ultra performance liquid chromatography-tandem mass spectrometry]. Se Pu. 2018 Aug 8;36(8):730-737. Chinese. doi: 10.3724/SP.J.1123.2018.02020. PMID: 30251495. 6: Kang D, Doudrick K, Park N, Choi Y, Kim K, Jeon J. Identification of transformation products to characterize the ability of a natural wetland to degrade synthetic organic pollutants. Water Res. 2020 Dec 15;187:116425. doi: 10.1016/j.watres.2020.116425. Epub 2020 Sep 19. PMID: 32979581.