PD 120697 is a dopamine antagonist. It is a novel class of compounds with central dopamine agonist properties. It has been identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests that include [3H]-haloperidol and [3H]-N-propylnorapomorphine binding, inhibition of striatal DA synthesis, inhibition of DA neuronal firing, inhibition of spontaneous locomotor activity, and reversal of reserpine-induced depression in rats.
MedKoo Cat#: 525829
Name: PD 120697
CAS#: 108351-91-3
Chemical Formula: C11H15N3S
Exact Mass: 221.0987
Molecular Weight: 221.32
Elemental Analysis: C, 59.69; H, 6.83; N, 18.99; S, 14.49
The following data is based on the product molecular weight 221.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
