Rosiglitazone activates PPARγ1 and PPARγ2 and selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARγ over PPARα and PPARδ in a cell-based reporter assay at 10 mM and can induce differentiation of C3H10T1/2 stem cells into adipocytes when used at a concentration of 1 µM.
MedKoo Cat#: 112061
Name: Rosiglitazone potassium
CAS#: 316371-84-3 (potassium)
Chemical Formula: C18H18KN3O3S
Exact Mass: 0.0000
Molecular Weight: 395.52
Elemental Analysis: C, 54.66; H, 4.59; K, 9.89; N, 10.62; O, 12.14; S, 8.11
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| Ethanol | 2.0 | 5.06 | |
| H2O | 1.0 | 2.53 |
The following data is based on the product molecular weight 395.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
