DSP 4 is a selective neurotoxin selective for noradrenergic neurons in the locus coeruleus noradrenergic system and capable of crossing the blood–brain barrier and cyclizes to a reactive aziridinium derivative that is accumulated into the noradrenergic nerve terminals via the noradrenaline transporter.
MedKoo Cat#: 524974
Name: DSP-4
CAS#: 62078-98-2 (free base)
Chemical Formula: C11H15BrClN
Exact Mass: 275.0076
Molecular Weight: 276.60
Elemental Analysis: C, 47.76; H, 5.47; Br, 28.89; Cl, 12.82; N, 5.06
The following data is based on the product molecular weight 276.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
