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MedKoo Cat#: 524878 | Name: CP-8668

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CP-8668 is an orally active nonsteroidal progesterone receptor modulator with tetrahydrobenzindolone skeleton. CP8668 showed selective affinity for human progesterone receptor equal in strength to other steroidal progestins.

Chemical Structure

CP-8668
CP-8668
CAS#209331-43-1

Theoretical Analysis

MedKoo Cat#: 524878

Name: CP-8668

CAS#: 209331-43-1

Chemical Formula: C21H30N2O4

Exact Mass: 374.2206

Molecular Weight: 374.47

Elemental Analysis: C, 67.35; H, 8.07; N, 7.48; O, 17.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CP-8668; CP8668; CP 8668; UNII-5371O2R79D.
IUPAC/Chemical Name
Carbamic acid, N-propyl-, (4aR,5R,6R,7R)-2,4,4a,5,6,7-hexahydro-7-methoxy-1,3,4a,5-tetramethyl-2-oxo-1H-benz(f)indol-6-yl ester
InChi Key
HHRZNPFAGIHNGP-ZEZXVUOJSA-N
InChi Code
InChI=1S/C21H30N2O4/c1-7-8-22-20(25)27-18-13(3)21(4)11-15-12(2)19(24)23(5)16(15)9-14(21)10-17(18)26-6/h9-10,13,17-18H,7-8,11H2,1-6H3,(H,22,25)/t13-,17+,18+,21+/m0/s1
SMILES Code
CCCNC(=O)O[C@@H]1[C@@H]([C@]2(CC3=C(C(=O)N(C3=CC2=C[C@H]1OC)C)C)C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 374.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kurihara K, Shinei R, Tanabe K, Tabata Y, Kurata Y, Hoshiko S, Okonogi T. Nonsteroidal progesterone receptor ligands (II); synthesis and SAR of new tetrahydrobenzindolone derivatives. Bioorg Med Chem. 2006 Jul 15;14(14):4862-78. Epub 2006 Mar 31. PubMed PMID: 16580209. 2: Tabata Y, Iizuka Y, Shinei R, Kurihara K, Okonogi T, Hoshiko S, Kurata Y. CP8668, a novel orally active nonsteroidal progesterone receptor modulator with tetrahydrobenzindolone skeleton. Eur J Pharmacol. 2003 Feb 7;461(1):73-8. Erratum in: Eur J Pharmacol. 2003 Apr 4;465(3):299. PubMed PMID: 12568918.