LY-344864 HCl | 1217756-94-9 | 5-HT1F receptor agonist

MedKoo Cat#: 526696 | Name: LY344864 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY344864 is a selective 5-HT1F receptor agonist with an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor. LY344864 possesses little affinity for the 56 other serotonergic and non-serotonergic neuronal binding sites examined. LY344864 was shown to be a full agonist producing an effect similar in magnitude to serotonin itself.

Chemical Structure

LY344864 HCl

CAS#1217756-94-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 526696

Name: LY344864 HCl

CAS#: 1217756-94-9 (HCl)

Chemical Formula: C21H23ClFN3O

Exact Mass: 387.1514

Molecular Weight: 387.88

Elemental Analysis: C, 65.03; H, 5.98; Cl, 9.14; F, 4.90; N, 10.83; O, 4.12

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Related CAS #

1217756-94-9 (HCl) 186544-26-3 (free base)

Synonym

LY-344864; LY344864; LY 344864; LY-344864 HCl; LY-344864 hydrochloride

IUPAC/Chemical Name

N-[(3R)-3-(Dimethylamino)-2,3,4,9-tetrahydro-1H-carbazol-6-yl]-4-fluorobenzamide hydrochloride

InChi Key

OKUHLSYESBLBCP-PKLMIRHRSA-N

InChi Code

InChI=1S/C21H22FN3O.ClH/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13;/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26);1H/t16-;/m1./s1

SMILES Code

O=C(NC1=CC2=C(NC3=C2C[C@H](N(C)C)CC3)C=C1)C4=CC=C(F)C=C4.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 387.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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