Synonym
Miroprofene; Miroprofeno; Miroprofenum; Antopen; Y-9213; Y 9213; Y9213; Miroprofen
IUPAC/Chemical Name
2-(4-(imidazo[1,2-a]pyridin-2-yl)phenyl)propanoic acid hydrochloride
InChi Key
OJGQFYYLKNCIJD-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
SMILES Code
CC(C1=CC=C(C2=CN3C=CC=CC3=N2)C=C1)C(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
266.30
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Sakaizumi K, Tomita H, Fujino M, Ikeuchi S, Senuma S. [Analgesic effects of miroprofen in post-extraction pain]. Shikai Tenbo. 1983 May;61(5):1021-6. Japanese. PubMed PMID: 6603669.
2: Katsu M, Hayakawa M, Kawai M, Fujimori I, Kohno M, Takeda Y, Sekita K, Ogihara K, Noguchi T, Iizuka K, Yamazaki S, Nakagawa H, Itoh S, Shimada S, Ohsuga H, Enomoto S, Matsuki Y, Seki K, Yamazaki F, Higashi F, Sasaki S. [Double blind controlled study of miroprofen in acute upper respiratory tract infections--comparison with ibuprofen]. Kansenshogaku Zasshi. 1982 May;56(5):434-53. Japanese. PubMed PMID: 6811679.
3: Mikashima H, Goto K. [Inhibitory effect of 2-(4-(2-imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's transl)]. Yakugaku Zasshi. 1982 Jan;102(1):99-103. Japanese. PubMed PMID: 7045328.
4: Maruyama Y, Anami K, Terasawa M, Goto K, Imayoshi T, Kadobe Y, Mizushima Y. Anti-inflammatory activity of an imidazopyridine derivative (miroprofen). Arzneimittelforschung. 1981;31(7):1111-8. PubMed PMID: 7196760.
5: Hori, Uemura M, Yaoi M, Mitsuda K. [Effects of Y-0213 (miroprofen) on postoperative pain in endodontics--double-blind test with placebos]. Shikai Tenbo. 1980 Nov;56(5):859-66. Japanese. PubMed PMID: 7020126.
