MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 406756 | Name: STK321130
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

STK321130, also known as FLT3-IN-2, is potent FLT3 inhibitor.

Chemical Structure

STK321130
STK321130
CAS#923562-23-6

Theoretical Analysis

MedKoo Cat#: 406756

Name: STK321130

CAS#: 923562-23-6

Chemical Formula: C21H16ClF3N4

Exact Mass: 416.1016

Molecular Weight: 416.83

Elemental Analysis: C, 60.51; H, 3.87; Cl, 8.50; F, 13.67; N, 13.44

Price and Availability

Size Price Availability Quantity
25mg USD 250.00 2 weeks
50mg USD 450.00 2 weeks
100mg USD 650.00 2 weeks
200mg USD 1,050.00 2 weeks
500mg USD 1,850.00 2 weeks
1g USD 2,650.00 2 weeks
2g USD 3,850.00 2 weeks
5g USD 5,850.00 2 weeks
Show More
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
STK321130; STK 321130; STK-321130; FLT3-IN-2.
IUPAC/Chemical Name
5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[4-(trifluoromethyl)phenyl]methyl]-2-pyridinamine
InChi Key
MFXPJGJSKHZZGC-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H16ClF3N4/c22-17-8-18-15(11-28-20(18)29-12-17)7-14-3-6-19(27-10-14)26-9-13-1-4-16(5-2-13)21(23,24)25/h1-6,8,10-12H,7,9H2,(H,26,27)(H,28,29)
SMILES Code
FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=C1)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
STK321130 is anFLT3, c-Kit, and c-FMS (IC50s = <1 μM for all).
In vitro activity:
To be determined
In vivo activity:
To be determined
Solvent mg/mL mM
Solubility
DMF:PBS (pH 7.2) (1:3) 0.3 0.60
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 416.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
To be determined
In vitro protocol:
To be determined
In vivo protocol:
To be determined