Synonym
Cgp 55802A; Cgp-55802A; Cgp55802A.
IUPAC/Chemical Name
3-Decenoic acid, 2-amino-10-((4-azido-2-hydroxy-3-iodobenzoyl)amino)-4-(phosphonomethyl)-, monosodium salt, (E)-
InChi Key
FASKOKIDAZVESF-LBEJWNQZSA-M
InChi Code
InChI=1S/C18H25IN5O7P.Na/c19-15-14(23-24-21)7-6-12(16(15)25)17(26)22-8-4-2-1-3-5-11(10-32(29,30)31)9-13(20)18(27)28;/h6-7,9,13,25H,1-5,8,10,20H2,(H,22,26)(H,27,28)(H2,29,30,31);/q;+1/p-1/b11-9+;
SMILES Code
O=C([O-])C(N)/C=C(CP(O)(O)=O)\CCCCCCNC(C1=CC=C(N=[N+]=[N-])C(I)=C1O)=O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
603.28
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Resink A, Villa M, Benke D, Möhler H, Balázs R. Regulation of the expression of NMDA receptor subunits in rat cerebellar granule cells: effect of chronic K(+)-induced depolarization and NMDA exposure. J Neurochem. 1995 Feb;64(2):558-65. PubMed PMID: 7830048.
2: Heckendorn R, Allgeier H, Baud J, Gunzenhauser W, Angst C. Synthesis and binding properties of 2-amino-5-phosphono-3-pentenoic acid photoaffinity ligands as probes for the glutamate recognition site of the NMDA receptor. J Med Chem. 1993 Nov 12;36(23):3721-6. PubMed PMID: 7902441.
3: Marti T, Benke D, Mertens S, Heckendorn R, Pozza M, Allgeier H, Angst C, Laurie D, Seeburg P, Mohler H. Molecular distinction of three N-methyl-D-aspartate-receptor subtypes in situ and developmental receptor maturation demonstrated with the photoaffinity ligand 125I-labeled CGP 55802A. Proc Natl Acad Sci U S A. 1993 Sep 15;90(18):8434-8. PubMed PMID: 8378316; PubMed Central PMCID: PMC47371.
4: Benke D, Marti T, Heckendorn R, Rehm H, Künzi R, Allgeier H, Angst C, Mohler H. Photoaffinity labeling of the NMDA receptor. Eur J Pharmacol. 1993 Jul 15;246(2):179-80. PubMed PMID: 8375463.
