PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) that down regulates targets of CBP in macrophages primary neurons.
MedKoo Cat#: 406726
Name: PF-CBP1 free base
CAS#: 1962928-21-7 (free base)
Chemical Formula: C29H36N4O3
Exact Mass: 488.2787
Molecular Weight: 488.63
Elemental Analysis: C, 71.28; H, 7.43; N, 11.47; O, 9.82
| Solvent | mg/mL | mM | comments | |
|---|---|---|---|---|
| Solubility | ||||
| DMF | 30.0 | 61.40 | ||
| DMF:PBS (pH 7.2) (1:1) | 0.5 | 1.02 | ||
| DMSO | 20.0 | 40.93 | ||
| Ethanol | 20.0 | 40.93 |
The following data is based on the product molecular weight 488.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
