BMS-183920 is a diacidic, potent angiotensin II receptor antagonist. BMS-183920 improved Caco-2 cell permeability and oral absorption in vivo, the relative extents of hydrolysis (bioactivation) vs metabolism of the prodrug determined whether a substantial improvement in bioavailability was achieved.
MedKoo Cat#: 524427
Name: BMS 183920
CAS#: 153072-33-4
Chemical Formula: C26H19N5O3
Exact Mass: 449.1488
Molecular Weight: 449.46
Elemental Analysis: C, 69.48; H, 4.26; N, 15.58; O, 10.68
The following data is based on the product molecular weight 449.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
