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MedKoo Cat#: 524423 | Name: BMS 180680

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS 180680 is antibacterial activity agent of new catechol-containing monobactam. BMS-180680 is often the most active compound against many species of the family Enterobacteriaceae, with MICs at which 90% of the isolates were inhibited.

Chemical Structure

BMS 180680
BMS 180680
CAS#142654-34-0

Theoretical Analysis

MedKoo Cat#: 524423

Name: BMS 180680

CAS#: 142654-34-0

Chemical Formula: C19H17N7O10S2

Exact Mass: 567.0478

Molecular Weight: 567.51

Elemental Analysis: C, 40.21; H, 3.02; N, 17.28; O, 28.19; S, 11.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
BMS 180680; BMS180680; BMS-180680; SQ 84,100;
IUPAC/Chemical Name
3-((((1-(2-Amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)methyl)-6,7-dihydroxy-2-quinoxalinecarboxylic acid (2R-(2alpha,3alpha(Z)))-
InChi Key
FAUHVXXXXAHABE-ZOUYLLLXSA-N
InChi Code
InChI=1S/C19H17N7O10S2/c1-6-13(17(30)26(6)38(33,34)35)24-16(29)14(10-5-37-19(20)23-10)25-36-4-9-15(18(31)32)22-8-3-12(28)11(27)2-7(8)21-9/h2-3,5-6,13,27-28H,4H2,1H3,(H2,20,23)(H,24,29)(H,31,32)(H,33,34,35)/b25-14-/t6-,13+/m0/s1
SMILES Code
n1c(c(nc2cc(c(cc12)O)O)CO\N=C(/C(=O)N[C@@H]1[C@@H](N(C1=O)S(=O)(=O)O)C)c1nc(sc1)N)C(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 567.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Schwan WR, Barker L, Brody LL. Differences in sensitivity to PA-1806 among iron transport mutants of Pseudomonas aeruginosa compared to Escherichia coli. Antimicrob Agents Chemother. 2000 Nov;44(11):3237-8. PubMed PMID: 11184229; PubMed Central PMCID: PMC101644. 2: Jagota NK, Chetram AJ, Nair JB. Determination of trace levels of hydrazine in the penultimate intermediate of a novel anti-infective agent. J Pharm Biomed Anal. 1998 Feb;16(6):1083-7. PubMed PMID: 9547713. 3: Fung-Tomc J, Bush K, Minassian B, Kolek B, Flamm R, Gradelski E, Bonner D. Antibacterial activity of BMS-180680, a new catechol-containing monobactam. Antimicrob Agents Chemother. 1997 May;41(5):1010-6. PubMed PMID: 9145861; PubMed Central PMCID: PMC163842.