Lysipressin Acetate | CAS#50-57-7 | vasopressor

MedKoo Cat#: 326649 | Name: Lysipressin Acetate

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lysipressin Acetate is an analog of Vasopressin, a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.

Chemical Structure

Lysipressin Acetate

CAS#83968-49-4

Theoretical Analysis

MedKoo Cat#: 326649

Name: Lysipressin Acetate

CAS#: 83968-49-4

Chemical Formula: C48H68N12O15S2

Exact Mass: 0.0000

Molecular Weight: 1117.26

Elemental Analysis: C, 51.60; H, 6.14; N, 15.04; O, 21.48; S, 5.74

Price and Availability

Size	Price	Availability	Quantity
10mg	USD 385.00	2 Weeks
50mg	USD 750.00	2 Weeks

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Related CAS #

22049-37-2 50-57-7 (free base)

Synonym

Lysipressin Acetate. L-Lysine vasopressin; Lypressin; Lysine pitressin; Lysine vasopressin; Lysine-ADH; Lysopressin; Lysylvasopressin; Oxytocin, 3-(L-phenylalanine)-8-L-lysine-; Postacton; Syntopressin; Vasophysin; Vasopressin-8-lysine; [8-Lysine]Vasopressin.

IUPAC/Chemical Name

H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond).

InChi Key

MSNBBKCTGMZLMA-DHSVNZEYSA-N

InChi Code

InChI=1S/C46H64N12O13S2.C2H4O2/c47-17-5-4-9-29(40(65)51-22-38(62)63)53-45(70)35-10-6-18-58(35)46(71)34-24-73-72-23-28(48)39(64)54-31(20-26-11-13-27(59)14-12-26)43(68)55-32(19-25-7-2-1-3-8-25)42(67)52-30(15-16-36(49)60)41(66)56-33(21-37(50)61)44(69)57-34;1-2(3)4/h1-3,7-8,11-14,28-35,59H,4-6,9-10,15-24,47-48H2,(H2,49,60)(H2,50,61)(H,51,65)(H,52,67)(H,53,70)(H,54,64)(H,55,68)(H,56,66)(H,57,69)(H,62,63);1H3,(H,3,4)/t28-,29-,30-,31-,32-,33-,34-,35-;/m0./s1

SMILES Code

O=C([C@@H](N)CSSC[C@H](NC1=O)C(N2[C@H](C(N[C@H](C(NCC(O)=O)=O)CCCCN)=O)CCC2)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC(N)=O)=O)CCC(N)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=C(O)C=C4.CC(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Lysipressin Acetate is an analog of Vasopressin, a powerful vasopressor used to modulate blood pressure.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	DMSO	100.0	89.50

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 1,117.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Rouille Y, Chauvet MT, Chauvet J, Acher R, Hadley ME. The distribution of lysine vasopressin (lysipressin) in placental mammals: a reinvestigation of the Hippopotamidae (Hippopotamus amphibius) and Tayassuidae (Tayassu angulatus) families. Gen Comp Endocrinol. 1988 Sep;71(3):475-83. PubMed PMID: 3192070. 2: Acher R, Chauvet J. Structure, processing and evolution of the neurohypophysial hormone-neurophysin precursors. Biochimie. 1988 Sep;70(9):1197-207. Review. PubMed PMID: 3147712. 3: Rouillé Y, Chauvet MT, Chauvet J, Acher R. Dual duplication of neurohypophysial hormones in an Australian marsupial: mesotocin, oxytocin, lysine vasopressin and arginine vasopressin in a single gland of the northern bandicoot (Isoodon macrourus). Biochem Biophys Res Commun. 1988 Jul 15;154(1):346-50. PubMed PMID: 3395337. 4: Chauvet J, Rouille Y, Chauvet MT, Acher R. Evolution of marsupials traced by their neurohypophyseal hormones: microidentification of mesotocin and arginine vasopressin in two Australian families, Dasyuridae and Phascolarctidae. Gen Comp Endocrinol. 1987 Sep;67(3):399-408. PubMed PMID: 3666414. 5: Acher R. The nonmammalian-mammalian transition through neurohypophysial peptides. Peptides. 1985;6 Suppl 3:309-14. PubMed PMID: 3831965. 6: Chauvet J, Hurpet D, Michel G, Chauvet MT, Acher R. Two multigene families for marsupial neurohypophysial hormones? Identification of oxytocin, mesotocin, lysipressin and arginine vasopressin in the North American opossum (Didelphis virginiana). Biochem Biophys Res Commun. 1984 Aug 30;123(1):306-11. PubMed PMID: 6477584. 7: Chauvet MT, Colne T, Hurpet D, Chauvet J, Acher R. A multigene family for the vasopressin-like hormones? Identification of mesotocin, lysipressin and phenypressin in Australian macropods. Biochem Biophys Res Commun. 1983 Oct 14;116(1):258-63. PubMed PMID: 6639661.