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MedKoo Cat#: 524258 | Name: AR-L 100 BS

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AR-L 100 BS is a bio-active chemical with cardiovascular effects and blood pressure.

Chemical Structure

AR-L 100 BS
CAS#77303-18-5

Theoretical Analysis

MedKoo Cat#: 524258

Name: AR-L 100 BS

CAS#: 77303-18-5

Chemical Formula: C16H17N3O3S

Exact Mass: 331.0991

Molecular Weight: 331.39

Elemental Analysis: C, 57.99; H, 5.17; N, 12.68; O, 14.48; S, 9.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AR-L 100 BS; AR-L-100BS; AR-L100 BS; BRN 0842454;
IUPAC/Chemical Name
2-(4-Methoxy-2-(2-(methylsulfinyl)ethoxy)phenyl)-1H-imidazo(4,5-b)pyridine
InChi Key
PKNOXLRZOZVZIP-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H17N3O3S/c1-21-11-5-6-12(14(10-11)22-8-9-23(2)20)15-18-13-4-3-7-17-16(13)19-15/h3-7,10H,8-9H2,1-2H3,(H,17,18,19)
SMILES Code
O=S(CCOC1=CC(OC)=CC=C1C2=NC3=NC=CC=C3N2)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Verrijk R, Vleeming W, van Rooij HH, Wemer J, Porsius AJ. Positive inotropic effects of milrinone, sulmazole and AR-L100 on isolated normal and infarcted hearts of the rat. Arch Int Pharmacodyn Ther. 1989 Jan-Feb;297:7-17. PubMed PMID: 2730243. 2: Hayes JS, Wyss VL, Wilson HC, Robertson DW, Kauffman RF. Molecular basis for the in vitro and in vivo cardiotonic activities of AR-L100. J Pharmacol Exp Ther. 1986 Nov;239(2):375-81. PubMed PMID: 3021955. 3: Diederen W, Kadatz R. Comparative cardiovascular effects of three benzimidazole derivatives, AR-L 57 BS, AR-L 100 BS, and AR-L 115 BS. Arzneimittelforschung. 1981;31(1a):141-6. PubMed PMID: 7195207.