MedKoo Cat#: 526615 | Name: MDK-5220
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDK-5220 is a potent ans selective Orexin2 receptor agonist. MDK-5220 has CAS#1796565-52-0, which has previously no designed code name. For the convenience of communication, MedKoo temporally names it as MDK-5220 (note: 5220 is the last four digit of its CAS#). MDK-5220 was reported in WO2015088000. MDK-5220 exhibits an orexin agonist activity and is expected to be useful as an excellent therapeutic or preventive agent for narcolepsy.

Chemical Structure

MDK-5220
MDK-5220
CAS#1796565-52-0

Theoretical Analysis

MedKoo Cat#: 526615

Name: MDK-5220

CAS#: 1796565-52-0

Chemical Formula: C32H34N4O5S

Exact Mass: 586.2250

Molecular Weight: 586.71

Elemental Analysis: C, 65.51; H, 5.84; N, 9.55; O, 13.63; S, 5.46

Price and Availability

Size Price Availability Quantity
100mg USD 850.00 2 weeks
200mg USD 1,450.00 2 weeks
500mg USD 2,150.00 2 weeks
1g USD 2,950.00 2 weeks
2g USD 3,850.00 2 weeks
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Related CAS #
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Synonym
MDK-5220; MDK 5220; MDK5220. Orexin2 receptor agonist.
IUPAC/Chemical Name
4'-methoxy-N,N-dimethyl-3'-(N-(3-((2-(3-methylbenzamido)ethyl)amino)phenyl)sulfamoyl)-[1,1'-biphenyl]-3-carboxamide
InChi Key
RHLMXWCISNJNDH-UHFFFAOYSA-N
InChi Code
InChI=1S/C32H34N4O5S/c1-22-8-5-10-25(18-22)31(37)34-17-16-33-27-12-7-13-28(21-27)35-42(39,40)30-20-24(14-15-29(30)41-4)23-9-6-11-26(19-23)32(38)36(2)3/h5-15,18-21,33,35H,16-17H2,1-4H3,(H,34,37)
SMILES Code
O=C(C1=CC(C2=CC=C(OC)C(S(=O)(NC3=CC=CC(NCCNC(C4=CC=CC(C)=C4)=O)=C3)=O)=C2)=CC=C1)N(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 586.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Nagase, H., et al.: PCT Int. Appl., WO 2015088000 A1 20150618 (2015)