Adamantoylcytarabine | CAS# 23113-01-1

MedKoo Cat#: 591067 | Name: Adamantoylcytarabine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adamantoylcytarabine is abioactive chemical.

Chemical Structure

Adamantoylcytarabine

CAS#23113-01-1

Theoretical Analysis

MedKoo Cat#: 591067

Name: Adamantoylcytarabine

CAS#: 23113-01-1

Chemical Formula: C20H27N3O6

Exact Mass: 405.1900

Molecular Weight: 405.45

Elemental Analysis: C, 59.25; H, 6.71; N, 10.36; O, 23.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Adam CA; Adamantoyl cytarabine

IUPAC/Chemical Name

2(1H)-Pyrimidinone, 4-amino-1-(5-O-(tricyclo(3.3.1.1.(3,7))dec-1-ylcarbonyl)-beta -D-arabinofuranosyl)- (9CI)

InChi Key

NMANUXYHRYVLDW-UITAOGKOSA-N

InChi Code

InChI=1S/C20H27N3O6/c21-14-1-2-23(19(27)22-14)17-16(25)15(24)13(29-17)9-28-18(26)20-6-10-3-11(7-20)5-12(4-10)8-20/h1-2,10-13,15-17,24-25H,3-9H2,(H2,21,22,27)/t10?,11?,12?,13-,15-,16+,17-,20?/m1/s1

SMILES Code

O=C1N=C(N)C=CN1[C@H]2[C@H]([C@@H]([C@@H](COC(C3(C4)CC5CC4CC(C5)C3)=O)O2)O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 405.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wechter WJ, Gish DT, Greig ME, Gray GD, Moxley TE, Kuentzel SL, Gray LG, Gibbons AJ, Griffin RL, Neil GL. Nucleic acids. 16. Orally active derivatives of ara-cytidine. J Med Chem. 1976 Aug;19(8):1013-7. PubMed PMID: 966247. 2: Gray GD, Mickelson MM. The immunosuppressive activity of adamantoyl cytarabine. 3. Immunosuppressive specificity in rats. Immunology. 1970 Sep;19(3):417-28. PubMed PMID: 5471827; PubMed Central PMCID: PMC1455691. 3: Gray GD, Mickelson MM. The immunosuppressive effects of adamantoyl cytarabine. II. Effects on skin allograft rejection by rats and mice. Transplantation. 1970 Feb;9(2):176-8. PubMed PMID: 4905927. 4: Greig ME, Gibbons AJ. Effects of cytarabine and adamantoyl cytarabine on experimental allergic encephalomyelitis in rats. Arch Int Pharmacodyn Ther. 1969 Dec;182(2):364-9. PubMed PMID: 5371187. 5: Gray GD, Mickelson MM, Crim JA. Immunosuppressive effects of adamantoyl cytarabine. I. Inhibition of hemagglutinin formation and graft versus host reactions in mice. Biochem Pharmacol. 1969 Sep;18(9):2163-9. PubMed PMID: 4390558.