MedKoo Cat#: 407326 | Name: CAY10683
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CAY10683, also known as Santacruzamate A, is a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. CAY10683 inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively.

Chemical Structure

CAY10683
CAY10683
CAS#1477949-42-0

Theoretical Analysis

MedKoo Cat#: 407326

Name: CAY10683

CAS#: 1477949-42-0

Chemical Formula: C15H22N2O3

Exact Mass: 278.1630

Molecular Weight: 278.35

Elemental Analysis: C, 64.73; H, 7.97; N, 10.06; O, 17.24

Price and Availability

Size Price Availability Quantity
50mg USD 300.00 2 Weeks
100mg USD 500.00 2 Weeks
250mg USD 850.00 2 Weeks
500mg USD 1,350.00 2 Weeks
1g USD 2,050.00 2 Weeks
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Related CAS #
No Data
Synonym
CAY10683; CAY-10683; CAY 10683; Santacruzamate A.
IUPAC/Chemical Name
ethyl (4-oxo-4-(phenethylamino)butyl)carbamate
InChi Key
HTOYBIILVCHURC-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H22N2O3/c1-2-20-15(19)17-11-6-9-14(18)16-12-10-13-7-4-3-5-8-13/h3-5,7-8H,2,6,9-12H2,1H3,(H,16,18)(H,17,19)
SMILES Code
O=C(NCCC1=CC=CC=C1)CCCNC(OCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 278.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pavlik CM, Wong CY, Ononye S, Lopez DD, Engene N, McPhail KL, Gerwick WH, Balunas MJ. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J Nat Prod. 2013 Nov 22;76(11):2026-33. doi: 10.1021/np400198r. Epub 2013 Oct 28. PubMed PMID: 24164245; PubMed Central PMCID: PMC3879121. (last updated: 4/20/2016)