MedKoo Cat#: 318550 | Name: Pivmecillinam Hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pivmecillinam hydrochloride is active against gram-negative organisms and used as for amdinocillin. Pivmecillinam is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic.

Chemical Structure

Pivmecillinam Hydrochloride
Pivmecillinam Hydrochloride
CAS#32887-03-9 (pivoxil HCl)

Theoretical Analysis

MedKoo Cat#: 318550

Name: Pivmecillinam Hydrochloride

CAS#: 32887-03-9 (pivoxil HCl)

Chemical Formula: C21H34ClN3O5S

Exact Mass: 0.0000

Molecular Weight: 476.03

Elemental Analysis: C, 52.99; H, 7.20; Cl, 7.45; N, 8.83; O, 16.81; S, 6.74

Price and Availability

Size Price Availability Quantity
10mg USD 250.00 2 Weeks
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
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Synonym
Pivmecillinam Hydrochloride; Melysin; Pivmecillinam (hydrochloride); UNII-48FX7N21H2; Pivmecilinamo clorhidrato [Spanish]; Pivmecillinam Hydrochloride; Pivoxil, Amdinocillin; Selexid;
IUPAC/Chemical Name
2,2-dimethylpropanoyloxymethyl (2S,5R,6R)-6-(azepan-1-ylmethylideneamino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrochloride
InChi Key
UHPXMYLONAGUPC-RSRKELGKSA-N
InChi Code
InChI=1S/C21H33N3O5S.ClH/c1-20(2,3)19(27)29-13-28-18(26)15-21(4,5)30-17-14(16(25)24(15)17)22-12-23-10-8-6-7-9-11-23;/h12,14-15,17H,6-11,13H2,1-5H3;1H/b22-12+;
SMILES Code
CC1(C(N2C(S1)C(C2=O)N=CN3CCCCCC3)C(=O)OCOC(=O)C(C)(C)C)C.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 476.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Anderson JD, Adams MA. Urinary excretion of mecillinam by volunteers receiving film-coated tablets of pivmecillinam hydrochloride. Chemotherapy. 1979;25(1):1-4. PubMed PMID: 217572. 2: Henrion R, Vige P. [Clinical study of pivmecillinam hydrochloride in lower urinary tract infections in pregnant women. Apropos of 44 cases]. Rev Fr Gynecol Obstet. 1987 Dec;82(12):761-4. French. PubMed PMID: 3324273. 3: Kjer JJ, Ottesen B. Pharmacokinetics of pivmecillinam hydrochloride in pregnant and non-pregnant women. Acta Pharmacol Toxicol (Copenh). 1986 Nov;59(5):430-1. PubMed PMID: 3811971. 4: Hagel RB, Waysek EH. Stability-indicating assay for pivmecillinam hydrochloride and pivmecillinam hydrochloride capsules. J Chromatogr. 1979 Oct 19;178(1):97-14. PubMed PMID: 231046.