Miconazole is an imidazole antifungal agent commonly applied topically to the skin or to mucous membranes to cure fungal infections. It works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. It can also be used against certain species of Leishmania protozoa which are a type of unicellular parasites that also contain ergosterol in their cell membranes. In addition to its antifungal and antiparasitic actions, it also has some antibacterial properties.
MedKoo Cat#: 318268
Name: Miconazole
CAS#: 22916-47-8 (free)
Chemical Formula: C18H14Cl4N2O
Exact Mass: 413.9860
Molecular Weight: 416.13
Elemental Analysis: C, 51.95; H, 3.39; Cl, 34.08; N, 6.73; O, 3.84
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
DMSO | 91.5 | 219.88 | |
Ethanol | 83.0 | 199.46 |
The following data is based on the product molecular weight 416.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |