Masupiridine, also known as SUVN-502, is a 5-HT6 receptor antagonist under evulation for treating Alzheimer’s disease, attention deficit hyperactivity disorder, Parkinson’s disease and schizophrenia. SUVN-502 is a pure 5-HT6 receptor antagonist with >1200-fold selectivity over 5-HT2A receptor with a superior profile that differentiates from competitor 5-HT6 antagonists. SUVN-502 has an excellent human pharmacokinetics for once a day treatment.
MedKoo Cat#: 522643
Name: Masupiridine free base
CAS#: 701205-60-9 (free base).
Chemical Formula: C21H24BrN3O3S
Exact Mass: 477.0722
Molecular Weight: 478.41
Elemental Analysis: C, 52.72; H, 5.06; Br, 16.70; N, 8.78; O, 10.03; S, 6.70
The following data is based on the product molecular weight 478.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
