Rabeximod, also known as ROB-803; is an immunomodulator agent. Rabeximod is effective in reducing disease severity of mouse models of autoimmune disorders. Rabeximod suppresses arthritis by preventing activation of inflammatory cells, most likely macrophages, in a time dependent fashion, downstream of TLR2 and TLR4 stimulation. Anti-inflammatory treatment of traumatic brain injury with Rabeximod reduces cerebral antigen presentation in mice.
MedKoo Cat#: 319916
Name: Rabeximod
CAS#: 872178-65-9
Chemical Formula: C22H24ClN5O
Exact Mass: 409.1669
Molecular Weight: 409.92
Elemental Analysis: C, 64.46; H, 5.90; Cl, 8.65; N, 17.09; O, 3.90
The following data is based on the product molecular weight 409.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
