Ioforminol | GE-145 | AN-113111 | CAS#1095110-48-7 | radiographic contrast

MedKoo Cat#: 319790 | Name: Ioforminol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ioforminol, also known as GE-145 and AN-113111, is a new low-osmolar dimeric radiographic contrast agent. GE-145 exhibits similar preclinical properties to other dimeric radiographic contrast media. In addition, the low osmolality enables an iso-osmolar formulation containing a significantly higher concentration of electrolytes than Visipaque.

Chemical Structure

Ioforminol

CAS#1095110-48-7

Theoretical Analysis

MedKoo Cat#: 319790

Name: Ioforminol

CAS#: 1095110-48-7

Chemical Formula: C33H40I6N6O15

Exact Mass: 1521.6820

Molecular Weight: 1522.14

Elemental Analysis: C, 26.04; H, 2.65; I, 50.02; N, 5.52; O, 15.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

GE-145; GE145; GE 145; AN-113111; AN113111; AN 113111; Ioforminol.

IUPAC/Chemical Name

5,5'-((2-hydroxypropane-1,3-diyl)bis(formylazanediyl))bis(N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide)

InChi Key

BFVVDRUCXCIALU-UHFFFAOYSA-N

InChi Code

InChI=1S/C33H40I6N6O15/c34-22-18(30(57)40-1-13(52)7-46)24(36)28(25(37)19(22)31(58)41-2-14(53)8-47)44(11-50)5-17(56)6-45(12-51)29-26(38)20(32(59)42-3-15(54)9-48)23(35)21(27(29)39)33(60)43-4-16(55)10-49/h11-17,46-49,52-56H,1-10H2,(H,40,57)(H,41,58)(H,42,59)(H,43,60)

SMILES Code

OC(CN(C1=C(I)C(C(NCC(O)CO)=O)=C(I)C(C(NCC(O)CO)=O)=C1I)C=O)CN(C2=C(I)C(C(NCC(O)CO)=O)=C(I)C(C(NCC(O)CO)=O)=C2I)C=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,522.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wistrand LG, Rogstad A, Hagelin G, Roed L, Oulie I, Gram A, Evans P, Rasmussen H, Grant D, Iveson P, Newton B, Thaning M. GE-145, a new low-osmolar dimeric radiographic contrast medium. Acta Radiol. 2010 Nov;51(9):1014-20. doi: 10.3109/02841851.2010.509739. PubMed PMID: 20849319. 2: Chai CM, Rasmussen H, Eriksen M, Hvoslef AM, Evans P, Newton BB, Videm S. Predicting cardiotoxicity propensity of the novel iodinated contrast medium GE-145: Ventricular fibrillation during left coronary arteriography in pigs. Acta Radiol. 2010 Nov;51(9):1007-13. doi: 10.3109/02841851.2010.504743. PubMed PMID: 20799918.