MedKoo Cat#: 319736 | Name: Tedatioxetine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tedatioxetine, also known as Lu AA24530, is an antidepressant agent. Tedatioxetine is reported to act as a triple reuptake inhibitor (5-HT > NE > DA) and 5-HT2A, 5-HT2C, 5-HT3 and α1A-adrenergic receptor antagonist. As of 2009, it was in phase II clinical trials for major depressive disorder.

Chemical Structure

Tedatioxetine
Tedatioxetine
CAS#508233-95-2 (free base)

Theoretical Analysis

MedKoo Cat#: 319736

Name: Tedatioxetine

CAS#: 508233-95-2 (free base)

Chemical Formula: C18H21NS

Exact Mass: 283.1395

Molecular Weight: 283.43

Elemental Analysis: C, 76.28; H, 7.47; N, 4.94; S, 11.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Lu AA24530; Lu AA-24530; Lu AA 24530; Tedatioxetine
IUPAC/Chemical Name
4-(2-(p-tolylthio)phenyl)piperidine
InChi Key
CVASBKDYSQKLSO-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H21NS/c1-14-6-8-16(9-7-14)20-18-5-3-2-4-17(18)15-10-12-19-13-11-15/h2-9,15,19H,10-13H2,1H3
SMILES Code
CC1=CC=C(SC2=CC=CC=C2C3CCNCC3)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Javelot H. [Psychopharmacology of anxiety and depression: Historical aspects, current treatments and perspectives]. Ann Pharm Fr. 2015 Oct 12. pii: S0003-4509(15)00110-8. doi: 10.1016/j.pharma.2015.09.001. [Epub ahead of print] Review. French. PubMed PMID: 26472602.